Therapeutic potential of targeting IL‐17 and IL‐23 in sepsis
نویسندگان
چکیده
منابع مشابه
Genetic epistasis of IL23/IL17 pathway genes in Crohn's disease.
BACKGROUND The IL23/IL17 pathway is pivotal in the development of chronic mucosal inflammation seen in Crohn's disease (CD). Genetic variants in the IL23R and IL12B have been associated with CD susceptibility. We investigated 10 genes within the IL23/IL17 pathway in a case-control study of 763 CD cases and 254 healthy controls. METHODS We identified a novel association in haplotypes in IL17A ...
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ژورنال
عنوان ژورنال: Clinical and Translational Medicine
سال: 2012
ISSN: 2001-1326,2001-1326
DOI: 10.1186/2001-1326-1-4